| First Author | Saito H | Year | 2005 |
| Journal | Biochem Biophys Res Commun | Volume | 331 |
| Issue | 4 | Pages | 1216-21 |
| PubMed ID | 15883005 | Mgi Jnum | J:98285 |
| Mgi Id | MGI:3577799 | Doi | 10.1016/j.bbrc.2005.04.043 |
| Citation | Saito H, et al. (2005) L7/Pcp-2-specific expression of Cre recombinase using knock-in approach. Biochem Biophys Res Commun 331(4):1216-21 |
| abstractText | We report a knock-in mouse expressing Cre recombinase from the translational initiation site (ATG) of the endogenous L7/Pcp-2 gene. The resulting Cre expression matches the pattern of L7/Pcp-2 expression that is restricted to cerebellar Purkinje cells and retinal cells. Moreover, the Cre mouse showed no significant behavioral abnormality. Thus, our novel Cre mouse can be used for generation of Purkinje cells and retinal cell-specific gene expression and/or knockout in mouse using the Cre/loxP system. |
