Primary Identifier | IPR024886 | Type | Family |
Short Name | BST2 |
description | Bone marrow stromal antigen 2, also known as tetherin, is an antiretroviral defence protein, that blocks release of enveloped virus from the cell surface [, , ]. Bst2/tetherin contains two membrane anchors which are employed to retain some enveloped viruses, including HIV-1, tethered to the plasma membrane in the absence of virus encoded antagonists []. Its expression is induced by interferon-alpha []and was originally linked to B cell development []. |