|  Help  |  About  |  Contact Us

Protein Domain : Bone marrow stromal antigen 2

Primary Identifier  IPR024886 Type  Family
Short Name  BST2
description  Bone marrow stromal antigen 2, also known as tetherin, is an antiretroviral defence protein, that blocks release of enveloped virus from the cell surface [, , ]. Bst2/tetherin contains two membrane anchors which are employed to retain some enveloped viruses, including HIV-1, tethered to the plasma membrane in the absence of virus encoded antagonists []. Its expression is induced by interferon-alpha []and was originally linked to B cell development [].

0 Child Features

0 Parent Features

2 Protein Domain Regions