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Protein Coding Gene : Prkar2a protein kinase, cAMP dependent regulatory, type II alpha

Primary Identifier  MGI:108025 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  19087
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including beta-2 adrenergic receptor binding activity; cAMP binding activity; and enzyme binding activity. Involved in modulation of chemical synaptic transmission. Located in cytoplasm. Part of cAMP-dependent protein kinase complex. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and leg. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha).
PHENOTYPE: Homozygous null mice are viable and appear healthy. They have normal growth and no deficits in locomotor activity, muscle strength, or exploratory behavior. [provided by MGI curators]
  • synonyms:
  • MGI:2143017,
  • 1110061A24Rik,
  • AI836829,
  • expressed sequence AI317181,
  • MGI:1913460,
  • Prkar2a,
  • MGD-MRK-37061,
  • MGI:2143127,
  • RII(alpha),
  • protein kinase, cAMP dependent regulatory, type II alpha,
  • expressed sequence AI836829,
  • AI317181,
  • RIKEN cDNA 1110061A24 gene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Mouse features --> Functions (GO terms)

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