Primary Identifier | MGI:6117837 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Tbx6 |
Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6NCrl)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An Y137A mutation was introduced in exon 3 and an FRT flanked pgk-hygro cassette was inserted in intron 2 via homologous recombination. Flp-mediated recombination removed the hygro cassette. RT-PCR indicates expression is initiated but not maintained in embryos. |