| Primary Identifier | MGI:1921123 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 73873 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable identical protein binding activity and microtubule binding activity. Acts upstream of or within cilium organization. Located in microtubule organizing center; photoreceptor connecting cilium; and photoreceptor inner segment. Is expressed in several structures, including aorta; brain; eye; reproductive system; and respiratory system. Used to study retinitis pigmentosa 28. Human ortholog(s) of this gene implicated in retinitis pigmentosa 28. Orthologous to human FAM161A (FAM161 centrosomal protein A). PHENOTYPE: Mice homozygous for a gene trapped allele show early loss of visual function associated with alterations in photoreceptor ciliary structure, abnormal photoreceptor outer segment morphology, microgliosis, and progressive retinal photoreceptor degeneration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
