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Publication : Genetic mapping of endogenous RD-114 retroviral sequences of domestic cats.

First Author  Reeves RH Year  1985
Journal  J Virol Volume  56
Issue  1 Pages  303-6
PubMed ID  4032538 Mgi Jnum  J:7994
Mgi Id  MGI:56463 Doi  10.1128/jvi.56.1.303-306.1985
Citation  Reeves RH, et al. (1985) Genetic mapping of endogenous RD-114 retroviral sequences of domestic cats. J Virol 56(1):303-6
abstractText  The RD-114 family of endogenous retroviral sequences in domestic cats has been shown to consist of approximately 20 copies of genetically divergent virogenes per haploid genome. The chromosomal localization for four endogenous sequences (RDV1-4) was accomplished by correlating the occurrence of specific feline chromosomes with diagnostic viral DNA fragments in a panel of cat X rodent somatic cell hybrids. Analysis of the hybrid panel revealed that endogenous RD-114 sequences are dispersed on multiple cat chromosomes, that certain proviral segments are polymorphic with respect to the presence or absence of virus, and that a restriction fragment characteristic of inducible RD-114 resides on a single feline chromosome (B3), probably at a single locus.
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