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Allele : Myf5<tm2(Myog)Jae> myogenic factor 5; targeted mutation 2, Rudolf Jaenisch

Primary Identifier  MGI:1933774 Allele Type  Targeted
Attribute String  Inserted expressed sequence, Null/knockout Gene  Myf5
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Deletion of all Myf5 coding sequences in exon 1 and replacement with the complete Myog coding region followed by a stop codon. A lox-P flanked neomycin cassette was also inserted downstream of the Myog coding region, but was removed via Cre-mediated recombination in ES cells prior to the generation of chimeric founder mice. This allele expresses a functional Myogenin protein under the control of the Myf5 promoter.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Myf5<myg-ki>,
  • Myf5<myg>,
  • Myf5<myg>,
  • Myf5<myg-ki>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories