|  Help  |  About  |  Contact Us

Protein Coding Gene : Pkd2l1 polycystic kidney disease 2-like 1

Primary Identifier  MGI:1352448 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  329064
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables several functions, including calcium ion binding activity; identical protein binding activity; and transmembrane transporter binding activity. Contributes to monoatomic cation channel activity and sour taste receptor activity. Involved in several processes, including cellular response to acidic pH; detection of chemical stimulus involved in sensory perception of sour taste; and protein tetramerization. Located in endoplasmic reticulum and plasma membrane. Part of calcium channel complex and receptor complex. Colocalizes with cell surface. Is expressed in cochlea; medulla oblongata; spinal cord; and tongue. Orthologous to human PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased chorda tympani nerve response to sour tastants. [provided by MGI curators]
  • synonyms:
  • BC046386,
  • PCL,
  • MGI:3040679,
  • polycystin-L,
  • polycystic kidney disease 2-like 1,
  • cDNA sequence BC046386,
  • Pkd2l1,
  • PKD2L,
  • MGI:1330816,
  • Pkdl,
  • TRPP3,
  • polycystic kidney disease (polycystin)-like homolog

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

3 Driver For