| Primary Identifier | MGI:2386963 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Kcnq2 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exons 3 through 5 were replaced by a neomycin selection cassette. The deleted region encompassed 429 bp encoding the second transmembrane domain and a portion of the pore region. While normal transcript was undetected by semi-quantitative RT-PCR analysis, low levels of an aberrant transcript in which exon 2 spliced to exon 6 were observed in homozygous mutant embryos. |
