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Allele : Shank1<tm1Shng> SH3 and multiple ankyrin repeat domains 1; targeted mutation 1, Morgan Sheng

Primary Identifier  MGI:3762757 Allele Type  Targeted
Attribute String  Null/knockout Gene  Shank1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to replace exons 14 and 15, encoding almost the entire PDZ domain, with a PGK-neomycin drug resistance cassette. The absence of protein product was confirmed by western blot analysis on forebrain membrane extracts.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

14 Publication categories

Trail: Allele