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Publication : The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein.

First Author  Wiedemann M Year  2001
Journal  Biochim Biophys Acta Volume  1520
Issue  3 Pages  247-50
PubMed ID  11566361 Mgi Jnum  J:71776
Mgi Id  MGI:2150792 Doi  10.1016/s0167-4781(01)00267-6
Citation  Wiedemann M, et al. (2001) The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein(1). Biochim Biophys Acta 1520(3):247-50
abstractText  The mouse Fgfrl1 gene codes for a novel cell surface protein that is closely related to the family of the FGF receptors. It contains three extracellular Ig C2 loops and an acidic box, which share 29-33% sequence identity (48-50% similarity) with FGF receptors 1-4. The intracellular portion of the novel protein, however, lacks a tyrosine kinase domain required for signal transduction by transphosphorylation. The gene for Fgfrl1 comprises six exons and is located on mouse chromosome 5 in close proximity to the Idua gene for L-iduronidase.
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