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Publication : Genetic and environmental correlations between brain weight and maze learning in inbred strains of mice and their F1 hybrids.

First Author  Padeh B Year  1976
Journal  Behav Genet Volume  6
Issue  1 Pages  31-41
PubMed ID  1252224 Mgi Jnum  J:35748
Mgi Id  MGI:83195 Doi  10.1007/BF01065676
Citation  Padeh B, et al. (1976) Genetic and environmental correlations between brain weight and maze learning in inbred strains of mice and their F1 hybrids. Behav Genet 6(1):31-41
abstractText  The relationships among body weight, cerebellum weight, cerebrum weight, maze-learning ability in a double T-maze, and discrimination learning in a Y-maze were studied in six inbred strains of mice and some of their F1 hybrids. The subjects were 131 male albino mice from 14 genotypic groups: five inbred groups and nine groups of crossbred offspring. Intra- and intergroup correlations were computed between all possible pairs of the anatomical and behavioral traits. A significant difference between the intragroup and intergroup correlations for any pair of variables was taken to indicate the presence of a genetic correlation between the two variables. On this basis, positive genetic correlations were indicated between T-maze learning ability and Y-maze learning ability, between body weight and T-maze learning ability, and possibility between body weight and both cerebellum and cerebrum weight and between cerebrum weight and T-maze learning ability. Negative genetic correlations were indicated between cerebellum weight and running time in both mazes and between total number of successes in the Y-maze and Y-maze running time.
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