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Protein Coding Gene : Ccl19 C-C motif chemokine ligand 19

Primary Identifier  MGI:1346316 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  24047
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables CCR7 chemokine receptor binding activity and chemokine activity. Involved in several processes, including positive regulation of T cell activation; positive regulation of cellular component organization; and positive regulation of macromolecule biosynthetic process. Located in external side of plasma membrane. Is expressed in Peyer's patch; inguinal lymph node; thymus; and thymus primordium. Orthologous to human CCL19 (C-C motif chemokine ligand 19).
PHENOTYPE: Homozygous mutation of this gene results in reduced T cell numbers. [provided by MGI curators]
  • synonyms:
  • Gm2023,
  • MGI:3779199,
  • 100039053,
  • CKb11,
  • exodus-3,
  • ENSMUSG00000078736,
  • C-C motif chemokine ligand 19,
  • predicted gene, ENSMUSG00000078736,
  • predicted gene, ENSMUSG00000078738,
  • MGI:3779198,
  • Scya19,
  • Ccl19,
  • small inducible cytokine A19,
  • MGI:3780192,
  • ENSMUSG00000078738,
  • predicted gene, 100039053,
  • predicted gene 2023

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For