| Primary Identifier | IPR030129 | Type | Family |
| Short Name | TMOD4 |
| description | The Tropomodulin (Tmod) family consist of four Tmods (Tmods 1-4) and three larger variants termed leiomodins (Lmods 1-3), which are expressed in a tissue-specific and developmentally regulated fashion []. Members of the Tmod family are actin filament pointed-end-capping proteins that regulate actin subunit association and dissociation from pointed ends in a tropomyosin-dependent manner [].Tropomodulin-4 (Tmod4) binds with F-actin []. Tmod1 and Tmod4 are sarcomeric Tmods that maintain thin filament stability and correctly specified thin filament lengths in cardiac muscles via their interactions with terminal tropomyosins and their ability to regulate actin subunit exchange at pointed ends []. |
