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Allele : Pkhd1<tm1Tjwt> polycystic kidney and hepatic disease 1; targeted mutation 1, Terry J Watnick

Primary Identifier  MGI:7546926 Allele Type  Targeted
Attribute String  Conditional ready, Epitope tag, No functional change Gene  Pkhd1
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 67 and an FRT-flanked PGK-neomycin cassette and second loxP site were inserted downstream of the 3’ UTR. In addition, a triple HA epitope-tag was inserted in frame at the C-terminus. The floxed region harbors the nuclear localization signal and the PC2-binding site and is a site for pathogenic mutations in humans.
  • mutations:
  • Insertion
  • synonyms:
  • Pkhd1<Flox67HA>,
  • Pkhd1<Flox67HA>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele