| Primary Identifier | MGI:2684881 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 195359 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of protein catabolic process; negative regulation of protein localization to nucleus; and protein modification by small protein conjugation. Predicted to be part of IkappaB kinase complex. Predicted to be active in cytoplasm. Orthologous to human TRIM40 (tripartite motif containing 40). PHENOTYPE: Mice homozygous for a knock-out allele exhibit enhanced antiviral immune responses and decreased susceptibility to viral infection induced morbidity/mortality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
