Primary Identifier | MGI:1920356 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 73106 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable heparin binding activity and serine-type peptidase activity. Predicted to be involved in proteolysis. Predicted to be located in azurophil granule lumen and extracellular space. Orthologous to human PRSS57 (serine protease 57). PHENOTYPE: Mice homozygous for a null allele display reduced levels of histamine and serotonin in mast cells resulting in defects in mast cell function. [provided by MGI curators] |