| Primary Identifier | MGI:1330861 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 13175 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables protein kinase activity. Involved in regulation of postsynapse assembly. Acts upstream of or within forebrain development; generation of neurons; and negative regulation of protein localization to nucleus. Located in postsynaptic density. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including eye; future brain; genitourinary system; gut; and nervous system. Orthologous to human DCLK1 (doublecortin like kinase 1). PHENOTYPE: Mice homozygous for a null allele lack the corpus callosum and hippocampal commissure and show aberrant interhemispheric axonal projections. Mice homozygous for a different null allele have normal gross brain architecture but show axonal and dendritic defects following knockdown of Dcx expression. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
