| First Author | Yogi Y | Year | 1989 |
| Journal | Nihon Rai Gakkai Zasshi | Volume | 58 |
| Issue | 4 | Pages | 235-40 |
| PubMed ID | 2489281 | Mgi Jnum | J:27853 |
| Mgi Id | MGI:75489 | Doi | 10.5025/hansen1977.58.235 |
| Citation | Yogi Y, et al. (1989) The experimental inoculation with Mycobacterium leprae in autoimmune mice: results of MRL/lpr mice inoculated into the right hind foot (continued). Nippon Rai Gakkai Zasshi 58(4):235-40 |
| abstractText | Using MRL/lpr, NOD and Crj:CD-1 (ICR) mice, inoculations of M. leprae were made into the right hind foot at a dose of 5.8 x 10(6) bacilli per foot in order to study the influence of the immunobiological characteristics of their mice on the growth of M. leprae. To summarize of the results, MRL/lpr mice showed the high susceptibility to M. leprae, while that of NOD mice were poor. In conclusion, the immunobiological characteristics of MRL/lpr, autoimmune mice bearing lpr gene had effect on the multiplication of M. leprae, this mouse is a suitable multibacillary model for the study of leprosy. |
