Primary Identifier | MGI:4437713 | Allele Type | Transgenic |
Attribute String | Inducible, Inserted expressed sequence | Gene | Tg(tetO-Akt1*)K8Lbjn |
Strain of Origin | C57BL/6 | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A dominant active form of Akt1 with a c-Src myristoylation sequence and a hemagglutinin tag added to the N-terminus was inserted behind a tetracycline-responsive promoter (tetO). Two lines were tested and displayed similar performance. Line K8 was studied further. |