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Publication : Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice.

First Author  Miyakawa T Year  1995
Journal  Brain Res Mol Brain Res Volume  28
Issue  2 Pages  349-52
PubMed ID  7723633 Mgi Jnum  J:23384
Mgi Id  MGI:71119 Doi  10.1016/0169-328x(94)00251-9
Citation  Miyakawa T, et al. (1995) Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice. Brain Res Mol Brain Res 28(2):349-52
abstractText  Mice with a mutation in fyn genes were examined for their susceptibility to acoustically primed audiogenic seizures. Homozygous mutant (fynz/fynz) mice were significantly more likely to have seizures and to show the stronger seizure syndrome (clonus). These results indicate that the susceptibility of acoustically primed audiogenic seizures is enhanced in the Fyn kinase deficient mice.
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