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Allele : Del(11Krt31c)2Tmm deletion, Chr 11, Thomas M Magin 2
Primary Identifier  MGI:6283859 Allele Type  Targeted
Attribute String  Null/knockout Gene  Del(11Krt31c)2Tmm
Transmission  Germline Strain of Origin  129S7/SvEvBrd
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted 5' and 3' of the keratin type I gene cluster. Cre mediated recombination deleted the entire cluster leaving a single loxP site from Krt222 to Krt17. The absence of the transcripts and gene products was confirmed by RT-PCR and immunofluorescence microscopy in homozygous embryos. ES cells carrying Krt31ctm1Tmm and Krt31ctm2Tmm and were used to create this deletion.
  • mutations:
  • Intergenic deletion,
  • Intragenic deletion
  • synonyms:
  • Del(11Krt222-Krt17)2Tmm,
  • KtyI<->,
  • Del2Tmm,
  • KtyI<->,
  • Del2Tmm,
  • Del(11Krt222-Krt17)2Tmm
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1 Feature

Trail: Allele

Genome

0 Expresses

76 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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