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Protein Domain : Fasciculation and elongation protein zeta 2

Primary Identifier  IPR015641 Type  Family
Short Name  FEZ_2
description  The gene unc-76 (unc, uncoordinated) is necessary for normal axonal bundling and elongation within axon bundles in Caenorhabditis elegans. Two human homologues, fasciculation and elongation protein zeta-1 and -2 (FEZ1 and 2) have been identified [].FEZ2 has been reported in rat, human and mouse. Similar to FEZ1, FEZ2 interactes with PKCzeta and induces neurite extension of PC12 cells when co-expressed with a constitutively active mutant of PKCzeta [].

0 Child Features

1 Parent Features

12 Protein Domain Regions