| Primary Identifier | IPR011680 | Type | Family |
| Short Name | FEZ |
| description | The first member of the FEZ (fasciculation and elongation protein zeta) family identified was unc-76, from C. elegans. The protein is necessary for normal axon fasciculation and is required for axon-axon interactions []. Later, two human homologues, FEZ1 and FEZ2, were identified []. FEZ1 and FEZ2 interact with PKCzeta and have been shown to induce neurite extension of PC12 cells when co-expressed with a constitutively active mutant of PKCzeta []. |
