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Publication : Stimulation of B-cell progenitors by cloned murine interleukin-7.

First Author  Namen AE Year  1988
Journal  Nature Volume  333
Issue  6173 Pages  571-3
PubMed ID  3259677 Mgi Jnum  J:14594
Mgi Id  MGI:62758 Doi  10.1038/333571a0
Citation  Namen AE, et al. (1988) Stimulation of B-cell progenitors by cloned murine interleukin-7. Nature 333(6173):571-3
abstractText  The events involved in the commitment and development of lymphoid lineage cells are poorly understood. We have used a recently described long-term culture system to establish a bioassay that can detect a novel growth factor capable of stimulating the proliferation of lymphoid progenitors. Using direct expression in mammalian cells we have isolated a complementary DNA clone encoding this novel haematopoietic growth factor, designated interleukin-7.
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