Primary Identifier | MGI:88302 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 268697 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity; enzyme binding activity; and patched binding activity. Acts upstream of or within in utero embryonic development; positive regulation of cell cycle; and positive regulation of fibroblast proliferation. Located in cytoplasm; membrane; and nucleus. Colocalizes with mitochondrial matrix. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; eye; and genitourinary system. Human ortholog(s) of this gene implicated in breast cancer and prostate cancer. Orthologous to human CCNB1 (cyclin B1). PHENOTYPE: Homozygous mutation of this gene is embryonic lethal. [provided by MGI curators] |