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Protein Coding Gene : Ccnb1 cyclin B1

Primary Identifier  MGI:88302 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  268697
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity; enzyme binding activity; and patched binding activity. Acts upstream of or within in utero embryonic development; positive regulation of cell cycle; and positive regulation of fibroblast proliferation. Located in cytoplasm; membrane; and nucleus. Colocalizes with mitochondrial matrix. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; eye; and genitourinary system. Human ortholog(s) of this gene implicated in breast cancer and prostate cancer. Orthologous to human CCNB1 (cyclin B1).
PHENOTYPE: Homozygous mutation of this gene is embryonic lethal. [provided by MGI curators]
  • synonyms:
  • cyclin B1,
  • cyclin B4,
  • MGD-MRK-2269,
  • MGC:18763,
  • Cycb-4,
  • Ccnb1-rs13,
  • cyclin B1, related sequence 13,
  • MGD-MRK-1814,
  • Ccnb1

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

4 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

40 Pathways

3 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For