Primary Identifier | MGI:5516591 | Allele Type | Chemically induced (ENU) |
Gene | Pcsk9 | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | ENU mutagenesis induced a point mutation that results in the amino acid substitution of a termination codon for tyrosine at position 119 (Y119X). The absence of protein expression was confirmed in the liver and plasma. |