Primary Identifier | MGI:3051989 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Pank3 |
Inheritance Mode | Not Specified | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The pGt1lxf gene trap vector, which integrated randomly into the first intron - which interrupts the coding sequence within the tenth codon - contains a splice acceptor sequence upstream of a Beta-geo (beta-galactosidase/neomycin phosphotransferase II fusion) reporter gene. Transcription from the endogenous promoter of the trapped gene and splicing of the message yields a fusion mRNA joining exogenous upstream exons to the Beta-geo coding sequence. |