| Primary Identifier | MGI:1313276 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 22317 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in SNARE complex assembly; regulation of synaptic vesicle fusion to presynaptic active zone membrane; and synaptic vesicle priming. Located in cell surface. Is active in glutamatergic synapse and neuromuscular junction. Is expressed in brain; cerebellum molecular layer; and ventral tegmental area. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome and spastic ataxia 1. Orthologous to human VAMP1 (vesicle associated membrane protein 1). PHENOTYPE: Mice homozygous for a spontaneous mutation show a 30% reduction in body size, do not attempt to right themselves, become visibly immobile and lay on their side by postnatal day 10, and display a general lack of purposeful movement and wasting leading to death prior to weaning. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
