| Primary Identifier | MGI:1856830 | Allele Type | Spontaneous |
| Gene | Aqp2 | Inheritance Mode | Recessive |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| description | Phenotypic Similarity to Human Syndrome: Congenital Obstructive Nephropathy (J:109463) |
| molecularNote | A mutation occurred in exon 4 converting the C at coding nucleotide 767 into a T (c.767C>T), resulting in a serine to leucine substitution (p.S256L). Apical accumulation of the protein is lost in the renal collecting ducts of homozygotes. |
