Primary Identifier | MGI:1924165 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 76915 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable double-stranded DNA binding activity. Predicted to be involved in homologous chromosome pairing at meiosis and reciprocal meiotic recombination. Predicted to act upstream of or within DNA recombination and meiotic cell cycle. Predicted to be located in nucleus. Is expressed in branchial arch; central nervous system; embryo; forelimb bud; and somite. Orthologous to human MND1 (meiotic nuclear divisions 1). PHENOTYPE: Homozygous mutants for this allele display defects in homologous chromosome synapsis and double-strand break repair. [provided by MGI curators] |