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Protein Coding Gene : Srcap Snf2-related CREBBP activator protein

Primary Identifier  MGI:2444036 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  100043597
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable ATP hydrolysis activity and histone binding activity. Predicted to be located in Golgi apparatus; nuclear body; and perinuclear region of cytoplasm. Predicted to be part of Swr1 complex. Is expressed in cerebral cortex ventricular layer; cortical plate; early conceptus; inner cell mass; and oocyte. Human ortholog(s) of this gene implicated in Floating-Harbor syndrome. Orthologous to human SRCAP (Snf2 related CREBBP activator protein).
PHENOTYPE: Mice homozygous for a null allele show impaired blastocyst development at E3.5 and early embryonic lethality. [provided by MGI curators]
  • synonyms:
  • MGI:3603830,
  • B930091H02Rik,
  • D030022P06Rik,
  • RIKEN cDNA F630004O05 gene,
  • Snf2-related CREBBP activator protein,
  • MGI:2445189,
  • RIKEN cDNA B930091H02 gene,
  • F630004O05Rik,
  • Srcap,
  • RIKEN cDNA D030022P06 gene

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