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Comment :

Type  MGI:General Description  topical application of 300 mM KCl induces a single spreading depression that causes hemiplegia, leaning, circling, and impaired coordination unlike in similarly treated wild-type mice KCl-induced cortical spreading depression propagates into the striatum unlike in wild-type mice but with lesser frequency and longer latencies than in Cacna1atm1Caya homozygotes corticaostriatal propogation of KCl-induced cortical spreading depression is greater in female mice than in male mice mice exhibit 1 or more recurrent spreading depressions following brief topical KCl application and extensive washing unlike in wild-type mice