Primary Identifier | MGI:6490616 | Allele Type | Transgenic |
Attribute String | Transactivator | Gene | Tg(Col2a1-tTA)HNono |
Strain of Origin | (C57BL/6 x SJL/J)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The 8.4kb construct incorporates the mouse Col2a1 promoter and a fragment of intron 1 ligated to a splice acceptor sequence followed by an internal ribosomeâentry site (IRES), tetracyclineâcontrolled transactivator (tTA), and the SV40 large T antigen polyadenylation signal. A single copy of the transgene was inserted 16 kb downstream of Peli2 on mouse Chromosome 14. Line H is the high expresser line. |