Primary Identifier | MGI:3056685 | Allele Type | Transgenic |
Attribute String | Reporter | Gene | Tg(GFAPGFP)14Mes |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
description | Bright fluorescence is observed in the cell bodies and processes of unfixed or fixed astrocyte preparations throughout the CNS of hemizygous mice. In addition retinal Mullers cells expressed the GFP transgene in response to degeneration of neighboring photoreceptors. |
molecularNote | The transgene contains a mutant form of Green Fluorescent Protein (hGFP-S65T) under the control of the human astrocyte-specific glial fibrillary acidic protein (GFAP) promoter. |