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Allele : Pou5f1<tm1Cgre> POU domain, class 5, transcription factor 1; targeted mutation 1, Centre for Genome Research

Primary Identifier  MGI:1933381 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Pou5f1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  An internal ribosome entry site-lacZ-neomycin resistance cassette (IRES-beta-geo) replaced sequences in exons 2-5 encoding the two DNA binding domains and the carboxy terminal transactivation site. Immunostaining did not detect wild-type protein in 3 of 15 2.5 day morulae from an intercross of heterozygous mutant animals.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Oct4-,
  • Oct4-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

8 Publication categories

Trail: Allele