| Primary Identifier | MGI:2384211 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Pparg |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| description | Homozygous mutant animals could not be recovered. The insertion of the PGK-neo cassette into an intronic region appears to disrupt the gene and results in homozygous embryonic lethality. |
| molecularNote | A loxP site was introduced 1 kb upstream of exon 2 and a floxed PGK-neo cassette was introduced 0.75 kb downstream of exon 2 via homologous recombination. Exon 2 encodes the DNA-binding domain of the gene. |
