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Protein Coding Gene : Prss55 serine protease 55

Primary Identifier  MGI:1918287 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  71037
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable serine-type endopeptidase activity. Involved in binding activity of sperm to zona pellucida and flagellated sperm motility. Located in acrosomal vesicle and plasma membrane. Orthologous to human PRSS55 (serine protease 55).
PHENOTYPE: Different knockout strategies result in inconsistent male reproduction phenotypes ranging from normal spermatogenesis and fertility to severe subfertility with astheno/teratozoospermia and low sperm ATP content to infertility with impaired sperm migration and sperm-egg recognition/binding defects. [provided by MGI curators]
  • synonyms:
  • Prss55,
  • 4933401F05Rik,
  • RIKEN cDNA 4933401F05 gene,
  • serine protease 55

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For