| Primary Identifier | MGI:1918957 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 71707 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable antioxidant activity and prenyltransferase activity. Predicted to be involved in menaquinone biosynthetic process; ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate; and vitamin K biosynthetic process. Predicted to be located in cytoplasm; membrane; and nucleus. Predicted to be active in Golgi membrane and endoplasmic reticulum. Used to study Schnyder corneal dystrophy. Human ortholog(s) of this gene implicated in Schnyder corneal dystrophy. Orthologous to human UBIAD1 (UbiA prenyltransferase domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality, reduced embryo size, failure to form the primitive streak, no mesoderm and inability to synthesize menaquinone 4. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
