Primary Identifier | MGI:107561 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 20347 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable chemorepellent activity and semaphorin receptor binding activity. Predicted to be involved in several processes, including axon guidance; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to act upstream of or within cell differentiation and nervous system development. Predicted to be located in extracellular region. Predicted to be active in plasma membrane. Is expressed in several structures, including genitourinary system; gut mucosa; nervous system; skeletal musculature; and tooth. Orthologous to human SEMA3B (semaphorin 3B). PHENOTYPE: Mice homozygous for one knock-out allele are viable and fertile with no obvious pathological abnormalities. Mice homozygous for a second knock-out allele exhibit improper positioning of a major brain commissural projection, the anterior commissure. [provided by MGI curators] |