| First Author | Swallow DM | Year | 1983 |
| Journal | Ann Hum Genet | Volume | 47 |
| Issue | Pt 1 | Pages | 9-17 |
| PubMed ID | 6301357 | Mgi Jnum | J:7039 |
| Mgi Id | MGI:55510 | Doi | 10.1111/j.1469-1809.1983.tb00965.x |
| Citation | Swallow DM, et al. (1983) Isozymes of rodent 5'-nucleotidase: evidence for two independent structural loci Umph-1 and Umph-2. Ann Hum Genet 47 Pt 1:9-17 |
| abstractText | Two distinct isozymes (UMPH-1 and UMPH-2) which hydrolyse pyrimidine 5'-nucleotides have been identified in mouse, rat and Chinese hamster tissues. One of these, UMPH-1 appears to be specific for pyrimidine 5'-nucleotides, whereas the other, UMPH-2 has a broader substrate specificity. UMPH-1 and UMPH-2 show differences in their expression in different tissues. The evidence suggests that UMPH-1 and UMPH-2 are coded by distinct structural gene loci, Umph-1 and Umph-2. These isozymes have not been identified in man, and it is suggested that they may have overlapping electrophoretic mobility. |
