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Protein Coding Gene : Usp15 ubiquitin specific peptidase 15
Primary Identifier  MGI:101857 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  14479
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables cysteine-type deubiquitinase activity. Acts upstream of or within regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator. Predicted to be located in cytosol and nuclear body. Predicted to be active in nucleus. Is expressed in incisor; nasal cavity epithelium; nervous system; submandibular gland primordium; and thymus primordium. Orthologous to human USP15 (ubiquitin specific peptidase 15).
PHENOTYPE: Mice homozygous for a knock-out allele or ENU induced allele exhibit resistance to pathological neuroinflammation. [provided by MGI curators]
  • synonyms:
  • MGI:2143588,
  • ubiquitin specific peptidase 15,
  • mKIAA0529,
  • E430033I05Rik,
  • granule cell antiserum positive 18,
  • 4921514G19Rik,
  • AI327321,
  • Usp15,
  • Gcap18,
  • expressed sequence AI327321,
  • RIKEN cDNA 4921514G19 gene,
  • RIKEN cDNA E430033I05 gene,
  • MGI:1918171,
  • MGD-MRK-18681
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