Primary Identifier | MGI:1353423 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 30046 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable DNA binding activity and DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; early conceptus; and genitourinary system. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human ZNF292 (zinc finger protein 292). PHENOTYPE: Mice homozygous for a null allele exhibit decreased ILC3 with increased susceptibility to C. rodentium infection. [provided by MGI curators] |