| Primary Identifier | MGI:2443667 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 320253 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. Predicted to act upstream of or within endocytosis. Predicted to be located in endosome and lysosome. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and integumental system. Orthologous to human MARCHF3 (membrane associated ring-CH-type finger 3). PHENOTYPE: Homozygous knockout causes de-repression of interleukin 1 beta activity, which results in increased cytokine levels and increased susceptibility to infection-induced mortality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
