Primary Identifier | IPR027326 | Type | Family |
Short Name | KIF20A |
description | Kinesin-like protein KIF20A was first identified as a binding partner for the rab6 GTPase involved in protein transport at the Golgi apparatus []. It was later found to be a mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. It is phosphorylated by PLK1 at Ser-528 during mitosis, creating a docking site for PLK1 and recruiting PLK1 at central spindle. It contains a kinesin-motor domain and has a microtubule plus end-directed motility []. |