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Protein Coding Gene : Mlf1 myeloid leukemia factor 1

Primary Identifier  MGI:1341819 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  17349
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables DNA binding activity. Involved in DNA-templated transcription and myeloid progenitor cell differentiation. Located in several cellular components, including ciliary basal body; motile cilium; and non-motile cilium. Is active in ciliary base. Is expressed in several structures, including brain; gonad; immune system; lung; and nasal cavity respiratory epithelium. Orthologous to human MLF1 (myeloid leukemia factor 1).
PHENOTYPE: Mice homozygous for a null allele exhibit a slight increased B cells in the spleen and decreased ex vivo thymocyte apoptosis susceptibility. [provided by MGI curators]
  • synonyms:
  • HLS7,
  • myeloid leukemia factor 1,
  • Mlf1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For