| Primary Identifier | MGI:3699359 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(MSR1-Pon1)1Road |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The coding region of mouse PON1 was placed under the control of the macrophage-specific human scavenger receptor A (MSR1) gene regulatory elements and the human growth hormone polyadenylation signal. Analysis of mRNA from transgenic mice showed that the construct was expressed only in circulating monocyte/macrophages and tissues containing resident macrophages (i.e., liver, lung, spleen, but not in heart, kidney, brain, or skeletal muscle). |
