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Publication : Fetal H-2 odortypes are evident in the urine of pregnant female mice.

First Author  Beauchamp GK Year  1994
Journal  Immunogenetics Volume  39
Issue  2 Pages  109-13
PubMed ID  8276453 Mgi Jnum  J:16131
Mgi Id  MGI:64221 Doi  10.1007/BF00188613
Citation  Beauchamp GK, et al. (1994) Fetal H-2 odortypes are evident in the urine of pregnant female mice. Immunogenetics 39(2):109-13
abstractText  The major histocompatibility complex (MHC) imparts to each mouse an individual urinary odor, called odortype, which reflects its MHC genotype. Perception of odortypes affects mate selection and embryonic implantation. Recent findings that odortypes are expressed as early as one day of age suggested that they might already be expressed in utero. We now report that at 9-12 days of gestation, odortypes specified by paternal (non-maternal) MHC haplotypes become apparent in maternal urine. Thus, odortypes are expressed in utero, can be sensed even before birth, and may serve in familial identification and communication.
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