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Publication : Heat shock proteins, tumor immunogenicity and antigen presentation: an integrated view.

First Author  Wells AD Year  2000
Journal  Immunol Today Volume  21
Issue  3 Pages  129-32
PubMed ID  10689300 Mgi Jnum  J:60906
Mgi Id  MGI:1354074 Doi  10.1016/s0167-5699(99)01558-3
Citation  Wells AD, et al. (2000) Heat shock proteins, tumor immunogenicity and antigen presentation: an integrated view. Immunol Today 21(3):129-32
abstractText  A broad range of studies has established that heat shock proteins (Hsps) potentially play a role in tumor immunosurveillance. Here, Andrew Wells and Miroslav Malkovsky highlight recent data that demonstrate a causal relationship between the expression of Hsps and tumor immunogenicity, and suggest several mechanisms by which Hsps might influence the capacity of a tumor to induce an immune response.
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