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Protein Coding Gene : Rangap1 RAN GTPase activating protein 1

Primary Identifier  MGI:103071 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  19387
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable GTPase activator activity; RNA binding activity; and enzyme binding activity. Involved in nuclear export. Located in perinuclear region of cytoplasm. Is expressed in several structures, including brain; genitourinary system; liver; lung; and primitive streak. Orthologous to human RANGAP1 (Ran GTPase activating protein 1).
PHENOTYPE: Homozygous mutation of this gene results in embryo arrest at the egg cylinder stage and lethality by E8.5. The appearance of the proamniotic cavity is delayed and epiblast cells surrounding the cavity are disorganized. Mesoderm and placental development is impaired. [provided by MGI curators]
  • synonyms:
  • Rangap1,
  • Fug1,
  • MGD-MRK-16762,
  • MGI:2146294,
  • failure to undergo gastrulation,
  • RAN GTPase activating protein 1,
  • expressed sequence C79654,
  • C79654,
  • MGD-MRK-23935

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

26 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For